Does it means that you have tried the "Reset & Rescan" option from within Logic Pro X Plug in Manager and does Logic X Plug in Manager gives you a msg like " failed validation " or is ANA 2 plug in not listed at all in the Plug In manager ??
If your mac Hardware is compatible, I will suggest to upgrade to latest High-Sierra 10.13.5 (17F77) because you're running the latest version of Logic X.
Next to that, be sure to use the latest version of ANA 2 which is ANA v2.0.81.zip to download from your account.
Aside being up to date, there could be issue with your HDD naming & format ( disk formatted with case sensitive option or special characters in disk name ) or macOSX Files Permission issue.
Here is an exhaustive topic about things you would like to troubleshoot, though this topic is related to ANA , the principle is the same beside the fact that the installation directory and the plugin name is different for ANA 2.
yourmacHDD/Library/Application Support/Sonic Academy/ANA 2
and for the plugins :