That's weird, could be a file & folder permission issue on MacOS, not sure, or something went wrong during the installation. You could give a try to repair files permission under MacOS and restart your Mac but if the issue persists, then you might have to perform a clean uninstall/reinstall of ANA 2.
If you need to do this, backup your Presets before :
All Factory Presets will be installed by default again, if you have any additional Presets Packs you can always download them from your S.A account and run the installers again.
Now if you have any User Presets, you need to make a back up and copy them somewhere else, presets themselves are stored in YourMacOSHDD/Library/Application Support/Sonic Academy/ANA 2/Presets/Sound Presets/User ( main Library, not the user one ) but if you imported your own samples to create presets you might have other files in different folders, therefore it's best to make a full Backup of your Presets folder YourMacOSHDD//Library/Application Support/Sonic Academy/ANA 2/Presets
Once you've done that check if you have a Sonic Academy folder inside your Applications folder, you should find an ANA 2 sub-folder with the manual & an uninstaller in there -> /Applications/Sonic Academy/ANA 2/Uninstaller
Run the uninstaller, be sure to download a fresh archive of ANA 2 as well as any Presets Packs you should need to re-install ( that's to make sure to avoid any corrupted downloads & archives, this happens ) and re-install ANA 2 & any Presets Packs you need.
Still suggest to check your macOS HDD & repair permissions before trying this.