It would be better to go through the manual uninstall/reinstall as a "clean" start point for any further troubleshooting yes.
If you're just using factory presets ( even with modified settings of course ) then simply make sure to use the SAVE AS option for each preset and save them into your User Presets folder. Then form ANA 2 menu, click on "Open User Preset Folder" and retrieve your Presets ( .SndPr files ) and keep a backup ( you can just copy the entire User Presets folder to a temporary location ) and save your DAW Project and you should be good to uninstall/reinstall without loosing anything ).
I'm now assuming that you're using Logic ? But still, what's the version you're running, and is your DAW up to date as well ?