Hi there @fmoridani
There's actually no settings allowing you to change the default presets install location directly from ANA 2.
Next to that, I would add that presets are usually not taking a huge amount of space on your system but if you wish to try to move those anyway, a workaround could be using "symlinks". Have a look a this topic to learn more about this. Don't mind if the topic is Kick 2 related, the idea & principal is exactly the same, so it should work fine. But once again, I think the free space has to be done somewhere else on your main HDD if you can, though I know it's not always that easy
Here is more about "Symlink" https://forums.sonicacademy.com/t/kick-2-preset-location/33155/10