Hi again Darren,
I've been through all of these and I think you're having an issue on your end during playback, especially when it comes to panning which is causing you to get an unbalanced stereo signal and a lower signal in the right channel.
You might have a Midi keyboard or controller and somehow sending Midi to LPX and triggering a Left Pan, please double check the LPX channel Pan Kob for ANA 2 Instrument track when browsing through presets and using maybe a Pitch or Mod Wheel on your controller ( or Midi Mapped Keyboard ).
Apart from this, I don't have issue with the Left signal getting increased or the right one getting reduced when playing each of those presets.
Better keep an eye on that Guy IMO
For the distortion, it's probably your own "sense" of how normal or not a preset might sound to you in that regard. Many of those presets are taking advantage of the Sampler Oscillator(s) next to the Main Osc(s), as well as Resonance settings on the filters and also onboard ANA 2 FX, EQ...etc.
ANA 2 is really fully featured when it comes to options and sound design, so to me all those presets are sounding this way on purpose, taking advantage of the synths capabilities.
Finally for the Strum GTR - Plucks - preset that has No Audio, this is another advanced feature of ANA 2 actually, if you edit the Chord Memory Device ( CMD ) settings, you will see that the STRUM feature is ON and this is midi mapped and assign to the mod-wheel. If you play one of the CMD programmed chord ( blue dotted keys on the virtual keyboard ) and slowly move the mod-wheel ( either via a midi keyboard or with your mouse on ANA 2 GUI ) it will " STRUM " the chords like a real guitar player is able to do. Another cool feature of ANA 2 to bring life into your sounds.